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A Rapid Vehicle Screen Approach for Formulating Liquid Filled Capsule of a Low Soluble Compound – 20

Released By Thermo Fisher Scientific Pharma Services

The objective of this study was to enhance the solubility and in-vitro dissolution/bioavailability of a low soluble (0.5 mg/mL) BCS Class II compound (API). A mixture approach enabled selection of excipients and to arrive at an optimal ratio based on the excipient properties.

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